Advances in Biochemical Techniques for Monitoring Emerging Infectious Diseases in Humans – Biological Times

Advances in Biochemical Techniques for Monitoring Emerging Infectious Diseases in Humans

Publication Date : 22/06/2024


Author(s) :

Muhammad Shahzaib , Jaweria Akhlaq.


Volume/Issue :
Volume 3
,
Issue 5
(06 - 2024)



Abstract :

Major global health challenges like infectious diseases are causing significant morbidity and mortality with approximately 25% of the 60 million annual deaths attributed to these diseases. However, microbial culture and immunological assays along with the face, speed, limitations , and specificity are the historic diagnostic methods used to hinder effective disease management. Molecular diagnostic techniques like Polymerase chain Reaction and high-throughput sequencing have revolutionized pathogen detection and offered rapid and precise identification. Diagnostic capabilities are enhanced through the innovation in point-of-care (POC) devices by offering rapid, on-site testing. The GeneXpert for tuberculosis and Human Immuno deficiency Virus are notable examples of Point of care . However, often lack full integration and automation indicating a need for further innovation in Point of care devices to achieve beneficial solutions. Additionally, electrochemical biosensors offer rapid, selective, and cost-effective virus detection. These biosensors identify the various viral biomarkers such as nucleic proteins,, nucleic acids, and antibodies essential for monitoring infections and guiding treatment. Infectious disease occurrences like Ebola,, zika ,and coronaviruses (e.g., SARS-CoV-2) highlight the necessity for advanced diagnostic tools


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