Author(s) :

Hamayun Khan.

Volume/Issue :

Abstract :

Vibrio cholera, a bacterium that causes cholera disease, has evolved over time, with new strains emerging and replacing old ones, highlighting the need for effective vaccines. Subunit vaccines, which use specific antigens to stimulate immune responses, offer a promising approach, with advances in proteomics and immunoinformatics driving innovation. Cholera vaccines have improved significantly, with subunit vaccines demonstrating exceptional efficacy rates and providing extended immune defense and broad-spectrum protection. Researchers are exploring new approaches, including multivalent vaccines, mucosal vaccines, and innovative delivery methods, to address challenges in global accessibility, immunosenescence, and vaccine effectiveness. The development of effective cholera vaccines is crucial to reducing the global burden of cholera and improving public health outcomes, particularly in low-income countries with inadequate sanitation and hygiene.

No. of Downloads :

4