Unraveling the Frontline Defense: Innate Immune Response to SARS-CoV-2 Infection

31-08-2024
Life Sciences
Duaa Hayat

Dr.Rais Ahmed, Muhammad Amir Haneef, Adnan Nawaz, Saba Seher.
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(08 - 2024)

Abstract :

The Coronavirus disease 2019 attained a pandemic status on March 11, 2020. The Coronaviruses devise immune system gears to target multiple aspects of innate immune system. Acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2) to prompt cytokine storm, prejudice interferon response and abolish presentation of antigen by Class I and class II MHC molecules. By understanding the recognition of SARS-CoV-2 and its immune evasion from immune system will probe in to a new perspective of viral clearance, vaccine formulation and immune therapeutic pattern and assessment. This review confers the connection of host innate immune response and immune evasion strategies of corona virus infection.

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