Advance Serological and Molecular Techniques for Diagnosis of Toxoplasmosis – Biological Times

Advance Serological and Molecular Techniques for Diagnosis of Toxoplasmosis

Publication Date : 09/11/2023


Author(s) :

Haleema Sadia, Muhammad Imran, Muhammad Waqas, Khizra Naeem, Imama Nasir, Iqra Hussain, Maqsood Ahmad.


Volume/Issue :
Volume 2
,
Issue 10
(11 - 2023)



Abstract :

Toxoplasmosis is a zoonotic disease which is prevalent globally. The causative agent of it is Toxoplasma gondii which is an intracellular protozoan parasite .This parasite is important in both medical and veterinary fields. Main route of transmission of disease is eating undercooked meat that contains viable tissues or drinking water and food that has been contaminated by oocysts. More than 60% populations are affected throughout the word with T. gondii. Abortion at third trimester is main clinical sign of disease in both humans and animals. Toxoplasmosis is traditionally diagnosed using etiological, immunological, and imaging techniques. Now-a-days, diagnosis is improved by using serological and molecular testing. Molecular testing amplifies the nucleic acid of parasites. PCR, a molecular technique is used for genetic characterization of T. gondii. Serological testing is the most common method of diagnosing toxicosis. An IgG test is used to determine if a person is infected. An IgM test is used to try to guess how long it will take to become infected, especially in pregnant women. IgM is used in combination with other tests, such as the avidity test. Clindamycin is drug of choice.


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