Author(s) :

Muhammad Bilal khadim .

Volume/Issue :

Abstract :

Glanders, caused by the bacterium Burkholderia mallei, is a highly contagious and often fatal disease primarily affecting horses, donkeys, and mules. It can also be transmitted to humans, albeit rarely. This abstract provides a concise overview of glanders, including its clinical manifestations, historical significance, and current challenges in prevention and treatment. Glanders has a long-standing history, with documented evidence dating back to ancient times, and has posed significant threats to both animal and human health throughout the ages. The disease is characterized by respiratory symptoms, skin lesions, lymph node enlargement, and systemic manifestations. Strict biosecurity measures, early detection, appropriate antibiotic therapy, and supportive care form the basis of treatment. Prevention involves implementing robust biosecurity protocols, surveillance programs, and research efforts for vaccines and diagnostics. Understanding the historical context, clinical findings, and strategies for prevention and treatment is crucial for minimizing the impact of glanders and safeguarding both human and animal populations from its devastating consequences.

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14