Crimean Congo Haemorrhagic Fever – Biological Times

Crimean Congo Haemorrhagic Fever

Publication Date : 27-06-2023

Author(s) :

Zuha Fatima , Muhammad Abdullah Qureshi , Muqadas , Muhammad luqman shabbir, Durr E Najaf .

Volume/Issue :
Volume 2
Issue 6
(06 - 2023)

Abstract :

Crimean Congo haemorrhagic fever is zoonotic disease spread by tick vector mostly of genus Hyalomma and caused by arbovirus Crimean Congo haemorrhagic fever virus (CCHFV). An RNA virus of family Bunyaviridae. Host range include humans, wide range of domestic and wild animals and birds. CCHFV transmits to humans by ticks and by animals and in humans, horizontal transmission by blood, saliva and semen has also been observed. In ticks, vertical transmission of virus occurs. Incubation period ranges from 3-13 days and mortality from 10-40%. Disease results in fever, headache, myalgia, photophobia, dizziness, abdominal pain, diarrhea, vomiting, rashes and hemorrhages etc but in severe cases multi organ failure, shock and finally death. CHF was first discovered in 1944 in Crimea in military staff. CCHF can be diagnosed by RT PCR, ELISA, IFA and rarely by virus isolation. Laboratory test results in leukopenia, thrombocytopenia and coagulation abnormalities. No specific treatment but supportive treatment is given in CCHF and antiviral agent (Ribavirin) to stop virus replication. Different preventive measures are taken to control CCHF like regular skin examination, tick repellent, use proper personal protective equipments and disinfectants etc.

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