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Gene editing is a novel genetic engineering technique that allows for exact modification of an organism's genome's particular gene sequence. Zinc-finger nucleases (ZFNs), transcription activator-like endonucleases (TALENs), and CRISPR/Cas9 systems have been used to alter endogenous genes in organisms over the past ten years due to the quick advancement of gene editing technology. Nowadays, a variety of animals, including mice, zebrafish, pigs, cattle, goats, sheep, rabbits, and primates, have been subjected to gene editing technologies. Traditional breeding often finds it challenging to develop agricultural animals to be disease-resistant, but gene editing technology has made this process simpler. In this paper, we provide an overview of the evolution and use of genome editing technologies in animal resistance breeding. Additionally, we go over the potential and outlooks of gene editing technology in disease resistance breedings.
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