Author(s) :

Noor Haider, saleha Tahir .

Volume/Issue :

Abstract :

The Clostridium species is responsible for gas gangrene, a lethal bacterial myonecrosis. Though it has been associated with higher rates of morbidity and mortality, it is fortunately rare in children. With the developments in veterinary and medical research, a significant amount of data regarding the factors influencing the onset, course, and results of necrotic illnesses caused by C. perfringens is gathering. Clostridial myonecrosis remains a major cause of sickness and mortality among people worldwide. Robust bacterial exotoxins are involved in both the severe tissue damage and the subsequent systemic symptoms, both directly and indirectly. The management trifecta of early identification, substantial surgical removal of necrotic tissue, and administration of antibiotics that inhibit the production of toxins remains the gold standard of care.

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