Celiac Disease; its Epidemiology, Pathogenesis, Diagnosis and Treatment
Publication Date : 30-11-2024
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Abstract :
Celiac disease is an autoimmune disorder triggered by the presence of gluten in diet. Mainly it damages the small intestine. Typical symptoms of celiac disease are chronic diarrhea, nausea, vomiting, constipation and foul-smelling stools. Celiac disease produces a series of complications like lactose intolerance, nutritional malabsorption and deficiency of vitamins. This disease is mostly common in children, but adults and older people can also be affected by this. The only effective treatment for this disease is a lifelong gluten-free diet. Celiac disease is easily confusable with other disorders, so a proper examination is needed. This confusion is also the reason for delayed diagnosis. Celiac disease is spread all around the globe with varying statistics. Its patients have genetic variants that are responsible for initiating autoimmune and inflammatory reactions. Serological blood testing is the primary technique in diagnosis followed by endoscopy and biopsies. Several researches are still underway to treat CD without diet.
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