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Postpartum Hemoglobinuria (PPH) is a metabolic disorder seen around the world effecting high producing buffaloes and cows mostly in their 3rd to 6th lactation or in pregnancy. This disease is critically dangerous, if left untreated it becomes highly lethal causing intravascular hemolysis and anemia. Along with phosphorous deficiency, low serum copper level and hemolytic toxin containing crops like cruciferous plants can trigger its progression. The soil low in phosphorous give rise to phosphorous deficient plants which further results in to hypophosphatemia. Elevated sulfur and lack of copper also raise the risk of PPH. The clinical signs include diminished appetite, red to dark brown color of urine (Red water name given because of this), pale mucous membrane, and reduced milk production. The buffaloes that are effected severally require blood transfusion and supportive therapies. Buffaloes can be treated with parental phosphorous supplements, IV administration of sodium acid phosphate, complemented by oral di-calcium phosphate, is quite effective.
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