Author(s) :

Saad Karim Abbasi, AHMAD RAZA, Taimor Badshah, Hamza Imtiaz , Muhammad Huzaifa Ahmad .

Volume/Issue :

Abstract :

Cancer is still one of the major diseases in the world and 2 million new cases are estimated to appear this year. Nature has provided the body with an immune system to combat these situations. The immune system consists of numerous cells throughout the body. But the one that stands out is Gamma Delta T Cell (γδ T cell) because of its unique ability to recognize and target cancer cells independently of MHC antigen presentation. Despite being less in circulation than other lymphocytes, they exhibit various mechanisms that help them eliminate cancer cells. These cells have been stimulated and expanded using different phospho-antigens and have shown promising anti-tumor abilities. Despite their potential, clinical results show limited efficacy of these cells. However, with recent advances in genetic engineering and synthetic biology, an exciting prospect for improving cancer treatment seems like the near future.

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