Neurocysticercosis Cysticercal Epilepsy: Understanding the Complex Relationship Between Tapeworm Cysts and Seizures. – Biological Times

Neurocysticercosis Cysticercal Epilepsy: Understanding the Complex Relationship Between Tapeworm Cysts and Seizures.

Publication Date : 10-02-2024


Author(s) :

Shizray Imtiaz Toor, Rao Zahid Abbas, Jovaria Khalid, M Saad Nauman, Hamza Aslam.


Volume/Issue :
Volume 3
,
Issue 2
(02 - 2024)



Abstract :

Infection with the swine tapeworm (Taenia solium) causes a significant global burden of disease, not only in terms of human health, but also in terms of economic hardship on smallholder pig farmers due to pig cysticercosis infection. In most underdeveloped nations, neurocysticercosis accounts for around 30% of all epilepsy cases. The immune diagnosis of cysticercosis is complicated and heavily impacted by the course of infection, disease burden, cyst location, and the host's immunological response. The primary strategy to immune-diagnosis should thus be to determine whether the serological results are aligned with the imaging-based diagnosis. In an enzyme-linked immune-electro transfer blot format, antibodies are detected using lentil lectin-purified parasite antigens, whilst antigens are detected using a monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA). Taenia solium’s life cycle, parasitology, and immunology is complicated. The 73rd World Health Assembly in November 2020 accepted the Organization's neglected tropical diseases plan for 2021-2030.


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