Author(s) :

Tehreem Nasir, Muhammad Zaid Khalil, Abdul Raheem.

Volume/Issue :

Abstract :

Canine parvovirus is a highly contagious viral disease of wild and domestic canids which is caused by Canine parvovirus type-2. The virus enters the host body through ingestion and replicates in the oropharynx from where it spreads to the other body’s organ via the bloodstream. The enteric form of the disease occurs due to the replication of the virus in intestinal crypts and it exhibits characteristic signs of acute hemorrhagic enteritis, foul-smelling bloody diarrhea, vomiting, dehydration, and ultimately leads to death. While cardiac form of the disease occurs due to scarring of the myocardium and is characterized by myocarditis and myocardial necrosis. Diagnosis of CPV is based on in-clinic assays and laboratory tests. Despite the provision of intensive care and rigorous supportive treatment, the survival rates of animals are still low. Control and prevention of disease is based on immunization via modified live vaccines but vaccine failure due to multiple reasons is also reported.

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