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There is increased hope that stem cell therapies, which have been successfully applied to patients, could one day be able to treat a variety of challenging diseases according to recent research. The therapeutic effectiveness of stem cells in damaged organs or tissues has improved recently because to the development of novel biomaterials that offers transplanted cells a stable cellular milieu. The use of synthetic and tissue-derived biomaterials in co-transplantation is revolutionizing our understanding of stem cell-based therapies. These biomaterials serve as a scaffold for stem cells and offer a unique opportunity to enhance their significant influences in regeneration and repair of tissue. Instead of existing naturally, induced pluripotent stem cells are created ("induced" or "reprogrammed") in culture from somatic cells by ectopically expressing specific pluripotency factors. Because iPSCs can be created from any patient or healthy individual, they are thought to be a crucial instrument for replacing diseased or damaged tissues in regenerative medicine. This article reviews the developments in stem cell research and discuss cell types that are either nearing clinical trials or are now being used in clinics.
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