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Pets frequently suffer from pyelonephritis, a dangerous bacterial infection of the kidneys and renal pelvis that primarily affects dogs and cats. Pregnant and immunocompromised animals are more likely to experience serious consequences, and it is most frequently linked to urinary tract infections. It manifests as flank pain, fever, and systemic disease. Despite the possibility of hematogenous spread, the illness is mainly caused by ascending infections from the lower urinary tract. Escherichia coli, Staphylococcus species, Proteus species, and Klebsiella species are common causal pathogens that are frequently made easier by immune suppression, diabetes mellitus, urinary tract anomalies, and catheterization. Clinical evaluation, urinalysis, culture, and, in more complex situations, imaging techniques like CT or ultrasound are also necessary for the diagnosis. In addition to supportive care, treatment entails the timely administration of antibiotics customized based on culture results. Addressing underlying risk factors, practicing good hygiene, and using prophylactic medication in high-risk situations like pregnancy are examples of preventive measures. For pets to have positive results and avoid chronic kidney impairment, early detection and effective therapy are essential.
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