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Antibiotic resistance (ABR) development continues to be a major worldwide health concern. Poultry accounts for a significant amount of the world's consumption of antibiotics. Despite significant efforts in prevention and management, bacterial illnesses such as avian pathogenic Escherichia coli, causing colibacillosis, and Clostridium perfringens, causing necrotic enteritis, continue to pose significant challenges for poultry producers in terms of economic losses and market limits. Antibiotics have been used to promote growth in addition to treating and preventing these illnesses. Consequently, these practices have been linked to the selection and dissemination of antibiotic-resistant bacteria. Producers that raise poultry are trying to reduce the administration of antibiotics (ABU) in an attempt to battle ABR. In this article, we will discuss antibacterial resistance, its mechanisms, and its impact on the environment, humans, and other animals. We will also discuss the challenges posed by ABR and its alternatives for the future.
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