Author(s) :

Maliha Manzoor, Aqsa Ashraf , Maria Aziz, Muhammad Taha Bin Husnain, Humaira Arshad.

Volume/Issue :

Abstract :

Human Immunodeficiency Virus attacks and weakens the immune system of the body in such a way that it causes severe infections and diseases. HIV weakens the immune system by destroying T cells. T cells that are destroyed by HIV are helper T cells or CD4 cells which causes a drop in white blood cells count. HIV has been a major global health challenge for many decades. HIV is capable of hiding in certain Cells of the body, and it remains inactive and undetectable for longer periods of time, which is why traditional therapies are unable to eliminate this because it is difficult to remove the virus from the body. Antiretroviral therapy allows people to live healthier and longer lives. The virus cannot be totally removed from the body, but it can be managed. Currently, researchers are employing sophisticated and promising RNA-based techniques. mRNA vaccines can be used to teach the immune system to identify and combat different strains of HIV more successfully. Two cutting-edge techniques being employed to target and disrupt the virus at a genetic level, including its hidden reservoirs, are RNA interference (RNAi) and CRISPR gene editing. These modern methods offer hope that, with additional research and Progress, HIV might eventually be prevented or even cured in addition to being under control.

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