Articles

Trichinella spiralis is a multicellular parasite that has zoonotic importance and causes trichinellosis in humans. It is transmitted from animals to humans through the eating of raw or poorly cooked meat contaminated with muscle larvae. Due to this parasite, meat food safety is disturbed. Initially, anthelmintic drugs are used for their control, but these have certain limitations. So, there is an urgent need for the development of new methods to control T. spiralis infection. Small interfering RNA is synthesized in the laboratory artificially. These are used in molecular biology to evaluate the function and characteristics of different genes. This technique was employed to find novel candidate targets for the development of vaccines. The whole sequence of T. spiralis is completed but the role of many genes is still unclear. RNAi is used to investigate different genes.