Articles

Brucellosis is a serious zoonotic disease posing a threat to animal welfare and causing huge economic losses since ancient times. Brucellosis transmission to humans through ingesting contaminated animal products or direct contact. Clinical manifestations include fever, fatigue, joint pain, myalgia, arthralgia, weight loss, endocarditis and neurological disorder. Abortion in the last trimester is the major sign of brucellosis. Diagnosis can be done by clinical signs, blood cultures, serological examinations and molecular approaches. Common risk factors include raw milk consumption, unhygienic slaughter of livestock, budgetary limitations and misdiagnosis. This article reviews current evidence on mechanism, epidemiology and clinical implications of brucellosis related pregnancy loss.