Articles

Corynebacterium pseudotuberculosis is a Gram-positive intracellular pathogen that causes various disease forms in livestock the most common of which are caseous lymphadenitis (CLA) and oedematous skin disease (OSD). Despite the etiological agent causing both conditions, the conditions differ very much in terms of clinical presentation, lesion characteristics, disease progression and diagnostic need. CLA is normally a chronic suppurative but with lymph nodes and OSD is an acute disease caused by toxins with diffuse subcutaneous edema. Proper distinction between the two conditions is essential to proper management of the disease, epidemiological monitoring and effective administration of the correct control measures. This review indicates the microbiological, clinical characteristics as well as methods of diagnosis between CLA and OSD.