Articles

Excessive lipid buildup in the liver is the hallmark of Non-Alcoholic Fatty Liver Disease (NAFLD) a rapidly expanding metabolic disorder. Oxidative stress, inflammation and dyslipidemia play significant roles in disease progression. Cynara cardunculus also known as artichoke, is a medicinal plant that is high in antioxidants, flavonoids and polyphenols. Its hepatoprotective, hypolipidemic and antioxidant properties have been shown in recent experimental investigations. In high-fat diet-induced NAFLD models, administration of Cynara cardunculus extract has been linked to improved liver enzyme levels, decreased lipid accumulation, improved lipid profile, and restoration of normal liver architecture. According to these results Cynara cardunculus may be a useful natural remedy for managing and preventing fatty liver diseas